Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616474 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL9840167 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL9840163 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL8927237 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL10616469 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL9750087 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL9750082 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL9750157 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL8927226 | 1.00 | APP (1.00) | APPCYP19A1MAOBMAOAMEN1 | |
| SCHEMBL4970063 | 0.97 | APP (0.94) | APPCYP19A1MAOBMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58222152-A | — | — | None | — | — | JP | disclosed |
| US-7858072-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-12-28 | — | — | US | disclosed |
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-30 | — | — | US | disclosed |
| US-5097022-A | Bisazo pigments for use in electrophotographic photoconductors | RICOH COMPANY, LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| US-4486519-A | HIGH PHOTOSENSITYIVITY AND FLEXIBILITY | RICOH COMPANY, LTD. (JP) | 1984-12-04 | — | — | US | disclosed |
| JP-S58222152-A | NOVEL DISAZO COMPOUND AND PRODUCTION THEREOF | RICOH CO LTD | 1983-12-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | APP, APBA1, PSEN1 | APP 1/4885CYP19A1 4622/4885MAOB 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.