Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 4/20 | 0.47 |
| ▸ | CHUK | O15111 | 4/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14534111 | 0.85 | PRKCI (0.53) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL239630 | 0.85 | NUDT1 (0.54) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL3088057 | 0.81 | PRKCI (0.58) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL1748621 | 0.81 | PRKCI (0.53) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL2602399 | 0.81 | PRKCI (0.53) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL1752655 | 0.81 | PRKCI (0.53) | PRKCIAXLIKBKBCHUKAURKB | |
| SCHEMBL28028674 | 0.80 | PRKCI (0.49) | PRKCIAXLIKBKBCHUKAURKB | |
| Hydrochloric Acid SCHEMBL4973929 | 0.79 | PRKCI (0.52) | PRKCIAXLIKBKBCHUKAURKB | |
| Hydrochloric Acid SCHEMBL31330471 | 0.79 | PRKCI (0.56) | PRKCIAXLIKBKBCHUKAURKB | |
| Hydrochloric Acid SCHEMBL4978077 | 0.79 | PRKCI (0.52) | PRKCIAXLIKBKBCHUKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003169-A | GPR40 receptor agonist, method for preparing same, and pharmaceutical composition containing same as active ingredient | 株式会社LG化学 | 2019-07-12 | — | — | CN | disclosed |