Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311301 | 1.00 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL618399 | 0.85 | KDM4E (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL618400 | 0.85 | KDM4E (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28311171 | 0.84 | ALDH1A1 (0.41) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28311187 | 0.84 | KDM4E (0.38) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28875444 | 0.82 | CHRNB4 (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28875445 | 0.82 | CHRNB4 (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL619025 | 0.82 | KDM4E (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1CHRNB4 | |
| SCHEMBL619024 | 0.82 | KDM4E (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1CHRNB4 | |
| SCHEMBL620293 | 0.81 | F2RL3 (0.44) | KDM4ECYP2D6CYP2C19CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |