Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394603 | 1.00 | HTR6 (0.57) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL30394843 | 0.89 | HTR6 (0.56) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL28311445 | 0.89 | HTR6 (0.56) | HTR6HTR1AHTR7HTR3AHTR3E | |
| SCHEMBL30395039 | 0.87 | HTR6 (0.55) | HTR6HTR1AHTR3AADRB1HTR2B | |
| SCHEMBL28311526 | 0.87 | HTR6 (0.55) | HTR6HTR1AHTR3AADRB1HTR2B | |
| SCHEMBL30394204 | 0.86 | HTR6 (0.56) | HTR6HTR1AHTR7 | |
| SCHEMBL28312401 | 0.86 | HTR6 (0.56) | HTR6HTR1AHTR7 | |
| SCHEMBL30394401 | 0.86 | HTR6 (0.71) | HTR6HTR1AHTR7 | |
| SCHEMBL28311460 | 0.86 | HTR6 (0.71) | HTR6HTR1AHTR7 | |
| SCHEMBL30394396 | 0.85 | HTR6 (0.55) | HTR6ADRB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117264-B | Phenyl sulfone derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-110117264-A | Phenyl sulfone derivative and its application on drug | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |