Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | DNA2 | P51530 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538267 | 0.89 | DNA2 (0.63) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL6090060 | 0.79 | DNA2 (0.56) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL29236598 | 0.79 | DNA2 (0.56) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL1017079 | 0.79 | DNA2 (0.56) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL30275708 | 0.79 | DNA2 (0.56) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL3066032 | 0.78 | DNA2 (0.66) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL8346957 | 0.78 | FBP1 (0.43) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL1277854 | 0.77 | DNA2 (0.83) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL3056048 | 0.77 | TRIM24 (0.57) | MAPTL3MBTL1NPC1MAPK1DNA2 | |
| SCHEMBL6538378 | 0.76 | DNA2 (0.63) | MAPTL3MBTL1NPC1MAPK1DNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101830-B | A kind of 3- replaces the preparation method of Oxoindole and derivative | 中国科学院成都生物研究所 | 2019-08-23 | — | — | CN | disclosed |