Toluene

Toluene

SCHEMBL28313163

C=CN.Cc1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.65
TSHR P16473 3/20 0.65
LMNA P02545 1/20 0.65
ALOX12 P18054 1/20 0.65
TDP1 Q9NUW8 3/20 0.42
TP53 P04637 2/20 0.42
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.40
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
CYP2D6 P10635 1/20 0.35
HIF1A Q16665 1/20 0.35
KIF11 P52732 1/20 0.33
HTT P42858 1/20 0.33
AKT1 P31749 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL392682 0.85 ACHE (0.69) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL527814 0.85 ACHE (0.69) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL9711191 0.82 ACHE (0.65) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL10610361 0.82 ACHE (0.65) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL27574114 0.82 ACHE (0.65) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL11006465 0.82 ACHE (0.65) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL270278 0.82 ACHE (0.65) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL27472683 0.82 ACHE (0.65) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL8943621 0.81 ACHE (0.85) ACHETSHRLMNAALOX12TDP1
Toluene SCHEMBL3396447 0.81 ACHE (0.85) ACHETSHRLMNAALOX12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110124359-A A kind of preparation method of modified organic silicon defoaming agent 陈朝亮 2019-08-16 CN claimed
CN-110124359-A A kind of preparation method of modified organic silicon defoaming agent 陈朝亮 2019-08-16 CN disclosed