Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24780773 | 0.78 | HTR6 (0.71) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL30261036 | 0.77 | HTR6 (0.52) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL16703805 | 0.76 | HTR6 (0.54) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL3644542 | 0.75 | HTR6 (1.00) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL26967483 | 0.74 | HTR6 (0.53) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL20561505 | 0.74 | HTR6 (0.58) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL25593890 | 0.74 | HTR6 (0.50) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL29728504 | 0.74 | HTR6 (0.65) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL724446 | 0.74 | HTR6 (0.65) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL29903480 | 0.73 | HTR6 (0.62) | HTR6DRD2HTR2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036004-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 希洛斯医药品股份有限公司 | 2019-07-19 | — | — | CN | disclosed |