SCHEMBL28313447

SCHEMBL28313447

CCCCCCCCCCCCCOC(=O)c1cc(S(=O)(=O)O)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 1/20 0.60
ALDH1A1 P00352 3/20 0.55
TSHR P16473 2/20 0.55
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPK1 P28482 1/20 0.52
ESR1 P03372 1/20 0.51
AKR1C4 P17516 1/20 0.51
AKR1C3 P42330 1/20 0.51
AKR1C2 P52895 1/20 0.51
AKR1C1 Q04828 1/20 0.51
KDM4E B2RXH2 3/20 0.49
KDM4A O75164 1/20 0.49
KDM4C Q9H3R0 1/20 0.49
HSD17B10 Q99714 2/20 0.49
POLB P06746 1/20 0.49
HPGD P15428 1/20 0.49
STS P08842 1/20 0.48
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9133233 0.89 S1PR3 (0.62) S1PR3ALDH1A1TSHRLMNATP53
SCHEMBL28152727 0.89 S1PR3 (0.62) S1PR3ALDH1A1TSHRLMNATP53
SCHEMBL10456235 0.85 HSD17B10 (0.45) S1PR3ALDH1A1TSHRKDM4EKDM4A
SCHEMBL27816715 0.83 CA12 (0.64) S1PR3ALDH1A1TSHRLMNAKDM4E
SCHEMBL15833742 0.83 S1PR3 (0.55) S1PR3ALDH1A1TSHRLMNATP53
SCHEMBL17883523 0.82 ALDH1A1 (0.47) S1PR3ALDH1A1KDM4EHSD17B10POLB
SCHEMBL10581365 0.82 CA12 (0.67) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL495935 0.82 CA12 (0.67) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL13422476 0.82 CA12 (0.67) ALDH1A1TSHRLMNATP53CYP3A4
SCHEMBL31125339 0.82 CA12 (0.67) ALDH1A1TSHRLMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110152714-A A kind of catalyst and its application method producing isobutyl amine and di-iso-butylmanice 浙江建业化工股份有限公司 2019-08-23 CN disclosed