Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314192 | 0.87 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL28314239 | 0.86 | ESR1 (0.59) | ESR1ESR2 | |
| SCHEMBL28313480 | 0.86 | ESR1 (0.50) | ESR1ESR2DRD2DRD1 | |
| SCHEMBL28043371 | 0.84 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL28313489 | 0.84 | ESR1 (0.47) | ESR1ESR2DRD2DRD1DRD4 | |
| SCHEMBL27706513 | 0.83 | ESR1 (0.49) | ESR1ESR2DRD2DRD1DRD4 | |
| SCHEMBL28875621 | 0.82 | ESR1 (0.48) | ESR1ESR2DRD2DRD1DRD4 | |
| SCHEMBL27803881 | 0.79 | CA12 (0.54) | ESR1ESR2 | |
| SCHEMBL27782259 | 0.79 | ESR1 (0.58) | ESR1ESR2DRD2DRD1DRD4 | |
| SCHEMBL6716401 | 0.79 | ESR1 (1.00) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988109-A | Inhibit the aminated compounds and application thereof of SSAO/VAP-1 | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |