SCHEMBL28314239

SCHEMBL28314239

O=CC1c2ccc(O)cc2CCN1c1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 19/20 0.59
ESR2 Q92731 17/20 0.59
GRIN1 Q05586 1/20 0.43
GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28314192 0.87 ESR1 (0.58) ESR1ESR2
SCHEMBL28313480 0.87 ESR1 (0.50) ESR1ESR2
SCHEMBL28313486 0.86 ESR1 (0.65) ESR1ESR2
SCHEMBL28313489 0.82 ESR1 (0.47) ESR1ESR2
SCHEMBL28875621 0.80 ESR1 (0.48) ESR1ESR2
SCHEMBL28043420 0.79 DRD2 (0.49) ESR1ESR2
SCHEMBL5103165 0.78 ESR1 (0.73) ESR1ESR2GRIN1GRIN2B
SCHEMBL5108754 0.77 ESR1 (0.71) ESR1ESR2
SCHEMBL27839468 0.76 ESR1 (0.37) ESR1ESR2
SCHEMBL28712494 0.76 CA1 (0.37) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109988109-A Inhibit the aminated compounds and application thereof of SSAO/VAP-1 广东东阳光药业有限公司 2019-07-09 CN disclosed