Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 8/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105772 | 0.84 | BIRC2 (0.45) | GNAO1GNAI3GNAI1BIRC2GLB1 | |
| SCHEMBL29509310 | 0.84 | BIRC2 (0.45) | GNAO1GNAI3GNAI1BIRC2GLB1 | |
| SCHEMBL22569563 | 0.82 | BIRC2 (0.46) | KCNH2BIRC2ACHEGBA1CHRM1 | |
| SCHEMBL7324387 | 0.82 | BIRC2 (0.46) | KCNH2BIRC2ACHEGBA1CHRM1 | |
| Hydrochloric Acid SCHEMBL21246945 | 0.80 | BIRC2 (0.45) | KCNH2BIRC2ACHEGBA1CHRM1 | |
| Hydrochloric Acid SCHEMBL21246944 | 0.80 | BIRC2 (0.45) | KCNH2BIRC2ACHEGBA1CHRM1 | |
| SCHEMBL3099250 | 0.79 | EBP (0.47) | GNAO1GNAI3GNAI1BIRC2 | |
| SCHEMBL3100830 | 0.77 | EBP (0.50) | GNAO1GNAI3GNAI1BIRC2 | |
| SCHEMBL4274108 | 0.77 | EBP (0.50) | GNAO1GNAI3GNAI1BIRC2 | |
| SCHEMBL31683714 | 0.77 | ACHE (0.53) | BIRC2ACHEGBA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |