Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.42 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036441 | 0.87 | MAPT (0.70) | ALDH1A1KDM4EMAPTPOLBRAD52 | |
| SCHEMBL10035939 | 0.87 | MAPT (0.56) | ALDH1A1KDM4EMAPTRAD52HTT | |
| SCHEMBL10036440 | 0.86 | MAPT (0.52) | ALDH1A1KDM4EMAPTPOLBRAD52 | |
| SCHEMBL10036378 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTPOLBRAD52 | |
| SCHEMBL2306566 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTPOLBRAD52 | |
| SCHEMBL328239 | 0.84 | MAPT (0.47) | ALDH1A1KDM4EMAPTRAD52HTT | |
| SCHEMBL24074321 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EMAPTRAD52HTT | |
| SCHEMBL10036431 | 0.83 | FGFR3 (0.51) | KDM4EMAPTRAD52PTK2BNR4A1 | |
| SCHEMBL6052489 | 0.83 | MAPT (0.50) | ALDH1A1KDM4EMAPTPOLBRAD52 | |
| Hydrochloric Acid SCHEMBL11751688 | 0.82 | MAPT (0.72) | ALDH1A1KDM4EMAPTPOLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041302-A | 2- amino -4- substituted pyridine derivative and its synthetic method and application | 南方医科大学 | 2019-07-23 | — | — | CN | disclosed |