Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.62 |
| ▸ | THRA | P10827 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313910 | 1.00 | THRB (0.62) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL28748404 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL2885452 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL7927891 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL27503295 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL24372243 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL7930191 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL10620500 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL27503643 | 0.98 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH | |
| SCHEMBL28805567 | 0.95 | THRB (0.64) | THRBTHRAKMT2ASMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105997967-B | Compound and composition for treating cancer | 普罗米蒂克医药SMT有限公司 | 2019-08-23 | — | — | CN | disclosed |