Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16981751 | 0.96 | ALDH1A1 (0.40) | GAAALDH1A1HTTTDP1TSHR | |
| SCHEMBL15234311 | 0.80 | ALDH1A1 (0.44) | GAAALDH1A1HTTTDP1TSHR | |
| Bicarbonate SCHEMBL27700582 | 0.78 | GAA (0.48) | GAAALDH1A1HTTTSHRMGAM | |
| SCHEMBL7059955 | 0.78 | ALDH1A1 (0.41) | GAAALDH1A1HTTTDP1TSHR | |
| Acetic Acid SCHEMBL27779067 | 0.77 | TSHR (0.48) | GAAALDH1A1HTTTDP1TSHR | |
| Acetic Acid SCHEMBL28107594 | 0.77 | GAA (0.46) | GAAALDH1A1HTTTSHRMGAM | |
| SCHEMBL20868607 | 0.76 | ALDH1A1 (0.40) | GAAALDH1A1HTT | |
| SCHEMBL16981750 | 0.76 | MGAM (0.33) | GAAMGAMSIMGAM2 | |
| Acetic Acid SCHEMBL9774425 | 0.75 | GAA (0.44) | GAAALDH1A1HTTTSHRMGAM | |
| SCHEMBL11970000 | 0.74 | HTT (0.42) | GAAALDH1A1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110100348-A | Electrolyte solution, electrochemical device, lithium ion secondary battery, and assembly | 大金工业株式会社 | 2019-08-06 | — | — | CN | disclosed |