Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.63 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314042 | 0.84 | PARP1 (0.61) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL23303966 | 0.79 | PARP1 (0.56) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL23303869 | 0.78 | PARP1 (0.55) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL20339795 | 0.77 | PARP1 (1.00) | PARP1PARP2MEN1KMT2A | |
| SCHEMBL11957594 | 0.76 | NPC1 (0.55) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL23303591 | 0.73 | PARP1 (0.49) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL23302805 | 0.73 | PARP1 (0.62) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL4074980 | 0.73 | MEN1 (0.65) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL11790805 | 0.72 | KMT2A (0.68) | PARP1PARP2MEN1KMT2AMAPT | |
| SCHEMBL14224507 | 0.72 | MAPK1 (0.58) | PARP1PARP2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167926-A | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS | 米托布里奇公司 | 2019-08-23 | — | — | CN | disclosed |