Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851211 | 0.80 | MEN1 (0.76) | KMT2AMEN1SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL11809344 | 0.80 | DRD2 (0.79) | KMT2AMEN1SIGMAR1MAPTKDM4E | |
| SCHEMBL4074980 | 0.79 | MEN1 (0.65) | KMT2AMEN1SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL12282111 | 0.78 | MEN1 (0.76) | KMT2AMEN1SMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL4072272 | 0.77 | MEN1 (0.84) | KMT2AMEN1SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL13936597 | 0.76 | MEN1 (0.73) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14224507 | 0.75 | MAPK1 (0.58) | KMT2AMEN1SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL11790812 | 0.75 | ALDH1A1 (0.54) | KMT2AMEN1SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL9581668 | 0.74 | MEN1 (0.71) | KMT2AMEN1SIGMAR1MAPTSMN1; SMN2 | |
| SCHEMBL27886023 | 0.74 | MEN1 (0.71) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936468-A | PSYCHOTROPIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-03 | — | — | US | disclosed |