Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488239 | 0.93 | PDGFRB (0.66) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL30616268 | 0.88 | PDGFRB (0.66) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL28313242 | 0.85 | PDGFRB (0.52) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL29812587 | 0.84 | PDGFRB (0.60) | PDGFRBPDGFRAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30448935 | 0.83 | PDGFRB (0.64) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL23640270 | 0.82 | PDGFRB (0.66) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL29535684 | 0.81 | PDGFRB (0.64) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL23924017 | 0.81 | PDGFRB (0.64) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL27894607 | 0.80 | PDGFRB (0.62) | PDGFRBPDGFRAALDH1A1KDM4EHPGD | |
| SCHEMBL27597858 | 0.79 | PDGFRB (0.57) | PDGFRBPDGFRAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049969-A | Quinolines, preparation method and its medical usage | 恩瑞生物医药科技（上海）有限公司 | 2019-07-23 | — | — | CN | disclosed |