Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47206 | 0.74 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28015510 | 0.73 | NOTUM (0.31) | — | |
| Pyrazine SCHEMBL27608305 | 0.71 | KMT2A (0.31) | — | |
| Ethoxycarbonyl Group SCHEMBL1332384 | 0.69 | — | — | |
| Ethoxycarbonyl Group SCHEMBL453 | 0.69 | — | — | |
| Ethoxycarbonyl Group SCHEMBL5306888 | 0.69 | ALDH1A1 (0.38) | — | |
| Benzene SCHEMBL18406222 | 0.67 | ALDH1A1 (0.32) | — | |
| Ethoxycarbonyl Group SCHEMBL3767822 | 0.67 | — | — | |
| Ethoxycarbonyl Group SCHEMBL4412187 | 0.67 | — | — | |
| Ethoxycarbonyl Group SCHEMBL5482235 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167935-A | The propionic acid that 3- as α V integrin inhibitors is substituted | 百时美施贵宝公司 | 2019-08-23 | — | — | CN | disclosed |