Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746229 | 0.81 | KDM4E (0.39) | TAAR1HTR2AHRH3 | |
| SCHEMBL4680155 | 0.79 | PRKCI (0.31) | TAAR1 | |
| SCHEMBL28314168 | 0.77 | TAAR1 (0.40) | TAAR1HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL7443632 | 0.76 | TYR (0.43) | — | |
| SCHEMBL28314165 | 0.75 | HTR2A (0.46) | HTR2AAOC3HTR1A | |
| SCHEMBL7019662 | 0.75 | TAAR1 (0.44) | TAAR1HTR2AHTR2CHTR2BAOC3 | |
| SCHEMBL27670907 | 0.75 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL463162 | 0.74 | TYR (0.43) | HTR2AHTR2C | |
| SCHEMBL63751 | 0.74 | — | — | |
| SCHEMBL28049282 | 0.73 | FFAR1 (0.38) | MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177796-A | Novel quinolinone derivative and pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy comprising said quinolinone derivative as active ingredient | 高丽大学校世宗产学协力团 | 2019-08-27 | — | — | CN | disclosed |