Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15008845 | 0.80 | TYR (0.39) | — | |
| SCHEMBL1476654 | 0.80 | ALDH1A1 (0.40) | TAAR1SLC6A4AOC3HTR2A | |
| SCHEMBL28336992 | 0.79 | TYR (0.40) | HTR2A | |
| SCHEMBL20801652 | 0.78 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL20801642 | 0.77 | — | — | |
| SCHEMBL14842441 | 0.76 | TAAR1 (0.31) | TAAR1 | |
| SCHEMBL11973125 | 0.76 | TERT (0.42) | TAAR1MPO | |
| SCHEMBL28314166 | 0.75 | TAAR1 (0.56) | TAAR1MPOAOC3HTR2AHTR2C | |
| SCHEMBL455192 | 0.73 | — | — | |
| SCHEMBL27830243 | 0.72 | TAAR1 (0.30) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358161-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Amgen Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055501-A2 | N-PYRIDYL CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMGEN INC (US) | 2002-07-18 | — | — | WO | disclosed |