SCHEMBL28314596

SCHEMBL28314596

CC(C)(C)c1ccc(C(C(=O)O)C(=O)O)cc1.[BaH2]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.52
NR1H4 Q96RI1 3/20 0.49
SRD5A2 P31213 1/20 0.47
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
FFAR1 O14842 1/20 0.44
HDAC1 Q13547 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
RARB P10826 1/20 0.43
RARG P13631 1/20 0.43
LMNA P02545 1/20 0.43
TYR P14679 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KIF11 P52732 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6951155 0.98 SRC (0.54) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL21268997 0.96 SRC (0.52) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL28314648 0.96 SRC (0.52) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL21269797 0.96 SRC (0.52) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL28314762 0.96 SRC (0.52) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL21269219 0.96 SRC (0.52) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL28314572 0.94 SRC (0.50) SRCNR1H4SRD5A2AKR1C3AKR1C2
SCHEMBL3591632 0.81 NR1H4 (0.50) NR1H4SRD5A2AKR1C3AKR1C2FFAR1
Iodide SCHEMBL31045512 0.79 NR1H4 (0.53) NR1H4SRD5A2AKR1C3AKR1C2FFAR1
SCHEMBL11238948 0.79 LMNA (0.56) NR1H4SRD5A2AKR1C3AKR1C2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172019-A The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic 印度石油有限公司 2019-08-27 CN claimed