Malonic Acid

Malonic Acid

SCHEMBL28314745

O=C(O)CC(=O)O.[KH].[Li]C(CC)CCCCC

nearest known ligand 0.44

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.44
FFAR1 O14842 2/20 0.43
FFAR4 Q5NUL3 1/20 0.43
PPARD Q03181 2/20 0.41
MAPT P10636 1/20 0.41
LCK P06239 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
AKR1B1 P15121 1/20 0.40
CA2 P00918 1/20 0.39
MAPK1 P28482 1/20 0.39
FAAH O00519 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL28314774 0.81 AKR1B1 (0.48) GPR84FFAR1FFAR4PPARDAKR1B1
SCHEMBL2178897 0.81
Malonic Acid SCHEMBL28727411 0.80 GPR84 (0.47) GPR84FFAR1FFAR4PPARDMAPT
Malonic Acid SCHEMBL28314744 0.79 CA1 (0.46) GPR84FFAR1CA2
Malonic Acid SCHEMBL28315663 0.78 GPR84 (0.50) GPR84FFAR1FFAR4PPARDMAPT
Malonic Acid SCHEMBL28315628 0.78 GPR84 (0.50) GPR84FFAR1FFAR4PPARDMAPT
Malonic Acid SCHEMBL28315812 0.78 GPR84 (0.50) GPR84FFAR1FFAR4PPARDMAPT
Malonic Acid SCHEMBL28315573 0.78 GPR84 (0.50) GPR84FFAR1FFAR4PPARDMAPT
Malonic Acid SCHEMBL28314326 0.78 GPR84 (0.50) GPR84FFAR1FFAR4PPARDMAPT
Malonic Acid SCHEMBL28314430 0.78 GPR84 (0.46) GPR84FFAR1FFAR4PPARDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172019-A The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic 印度石油有限公司 2019-08-27 CN disclosed