Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668619 | 0.78 | EPHX2 (0.42) | — | |
| SCHEMBL20069704 | 0.77 | RET (0.37) | RET | |
| SCHEMBL20907631 | 0.77 | TSHR (0.37) | RET | |
| SCHEMBL20147470 | 0.76 | RET (0.39) | RET | |
| SCHEMBL20158854 | 0.74 | RET (0.38) | RET | |
| SCHEMBL20147975 | 0.74 | RET (0.38) | RET | |
| SCHEMBL28823557 | 0.70 | — | — | |
| SCHEMBL20070046 | 0.69 | CYP1A2 (0.35) | RET | |
| SCHEMBL29263153 | 0.69 | — | — | |
| SCHEMBL28785233 | 0.68 | DPP4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |