⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056907 | 0.78 | CHRM3 (0.36) | — | |
| SCHEMBL27774462 | 0.77 | DPP4 (0.33) | — | |
| SCHEMBL28785233 | 0.77 | DPP4 (0.33) | — | |
| SCHEMBL27795393 | 0.77 | DPP4 (0.33) | — | |
| SCHEMBL27650347 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL18423086 | 0.74 | USP2 (0.47) | — | |
| SCHEMBL27868908 | 0.73 | RBP1 (0.33) | — | |
| SCHEMBL27789518 | 0.73 | — | — | |
| SCHEMBL28268984 | 0.73 | — | — | |
| SCHEMBL28030208 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624053-B2 | Ras inhibitors | Revolution Medicines, Inc. (US) | 2026-05-12 | — | — | US | disclosed |
| US-20260070930-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT | 2026-03-12 | — | — | US | disclosed |
| US-20250388608-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2025-12-25 | — | — | US | disclosed |
| US-20250145643-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2025-05-08 | — | — | US | disclosed |
| CN-118234731-A | RAS inhibitors | 锐新医药公司 | 2024-06-21 | — | — | CN | disclosed |