Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620860 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNACA12CA2CA9 | |
| SCHEMBL28316196 | 0.75 | LMNA (0.52) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL12479725 | 0.75 | LMNA (0.52) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL15740308 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL9432745 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL7826827 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL25619858 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHPGDNPSR1KDM4E | |
| SCHEMBL4573738 | 0.69 | LMNA (0.39) | SMN1; SMN2LMNA | |
| SCHEMBL29227708 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHPGDNPSR1KDM4E | |
| SCHEMBL9432620 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209326137-U | Cooling device is used in 4,6- of one kind dimethoxy-dimesyl pyrimidine preparation | 江西聚合医药科技有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-209326137-U | Cooling device is used in 4,6- of one kind dimethoxy-dimesyl pyrimidine preparation | 江西聚合医药科技有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-209326137-U | Cooling device is used in 4,6- of one kind dimethoxy-dimesyl pyrimidine preparation | 江西聚合医药科技有限公司 | 2019-08-30 | — | — | CN | disclosed |