Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280876 | 0.85 | PROKR1 (0.47) | MEN1KMT2APROKR1FASNALDH1A1 | |
| SCHEMBL30280803 | 0.82 | HSD11B1 (0.48) | MEN1KMT2APROKR1HSD11B1FASN | |
| SCHEMBL30280881 | 0.79 | PROKR1 (0.55) | PROKR1HSD11B1FASNALDH1A1TP53 | |
| SCHEMBL4180599 | 0.77 | FASN (0.60) | PROKR1FASNDRD4 | |
| SCHEMBL30280978 | 0.76 | FASN (0.52) | HSD11B1FASNDRD4CYP2D6CYP2C9 | |
| SCHEMBL4191691 | 0.75 | FASN (0.67) | FASN | |
| SCHEMBL30280844 | 0.75 | FASN (0.57) | FASN | |
| SCHEMBL30281041 | 0.75 | FASN (0.55) | FASN | |
| SCHEMBL30280729 | 0.74 | FASN (0.49) | FASN | |
| SCHEMBL30280849 | 0.74 | FASN (0.54) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177551-A | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V生物科学股份有限公司 | 2019-08-27 | — | — | CN | disclosed |