Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316073 | 0.83 | CDC7 (0.33) | CDC7DBF4KDM4EKMT2AL3MBTL1 | |
| SCHEMBL28315330 | 0.83 | CDC7 (0.33) | CDC7DBF4 | |
| SCHEMBL27525348 | 0.83 | CDC7 (0.49) | CDC7DBF4KDM4EKMT2AHDAC3 | |
| SCHEMBL28316079 | 0.83 | CDC7 (0.33) | CDC7DBF4HDAC3HDAC4HDAC1 | |
| SCHEMBL23123491 | 0.76 | — | — | |
| SCHEMBL5473276 | 0.76 | — | — | |
| SCHEMBL28315311 | 0.73 | ACACB (0.34) | — | |
| SCHEMBL1581406 | 0.72 | ALDH1A1 (0.42) | KMT2AMAPT | |
| SCHEMBL3614873 | 0.70 | — | — | |
| SCHEMBL28316604 | 0.69 | ACACB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458941-B | Use the manufacturing method of the isothiazole compounds of ether compound | 组合化学工业株式会社 | 2019-08-30 | — | — | CN | disclosed |