Sugi Predict

Sugi Predict / Compounds / SCHEMBL28316619

SCHEMBL28316619

SCHEMBL28316619

CC(C)(C)c1ccc(-c2cc(-c3ccccc3)cc(-c3cc(F)cc(F)c3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.43
▸ MAPT P10636 2/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ DHODH Q02127 3/20 0.42
▸ KIF11 P52732 2/20 0.41
▸ CYP19A1 P11511 1/20 0.41
▸ LMNA P02545 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ TNF P01375 1/20 0.39
▸ NOD1 Q9Y239 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ TNKS O95271 1/20 0.39
▸ PARP1 P09874 1/20 0.39
▸ TNKS2 Q9H2K2 1/20 0.39
▸ ADORA1 P30542 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13203368 0.89 MEN1 (0.49) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL19735240 0.89 MEN1 (0.51) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL19862793 0.89 MEN1 (0.51) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL18326879 0.88 CYP19A1 (0.47) MEN1KMT2ADHODHKIF11CYP19A1
SCHEMBL13203384 0.86 MEN1 (0.47) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL21644725 0.84 MPL (0.40) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL30497939 0.84 MPL (0.40) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL4547010 0.84 CYP19A1 (0.53) KDM4EMAPTMEN1KMT2ADHODH
SCHEMBL13253728 0.80 KIF11 (0.50) MAPTMEN1KMT2ADHODHKIF11
SCHEMBL23959669 0.80 MEN1 (0.49) KDM4EMAPTMEN1KMT2AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088228-B Luminescent gold (III) compounds containing cyclometallated tridentate ligands with aryl auxiliary ligands for organic light emitting devices and preparation thereof 香港大学 2023-08-15 — — CN disclosed
US-11362287-B2 Luminescent cyclometalating tridentate ligand-containing gold(III) compounds with aryl auxiliary ligands for organic light-emitting devices and their preparation thereof THE UNIVERSITY OF HONG KONG (HK) 2022-06-14 — — US disclosed
CN-110088228-A Luminescent gold (III) compound containing Cyclometalated tridentate ligand and its preparation for organic light emitting apparatus with aryl assistant ligand 香港大学 2019-08-02 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11362287-B2 Luminescent cyclometalating tridentate ligand-containing gold(III) compounds with aryl auxiliary ligands for organic light-emitting devices and their preparation thereof CBR3, NR4A3, NR2C2 KDM4E 3629/4885MAPT 3580/4885MEN1 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.