SCHEMBL2831672

SCHEMBL2831672

C1CCC1.NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 10/20 0.64
TSHR P16473 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
POLB P06746 1/20 0.56
CYP3A4 P08684 1/20 0.56
MAPT P10636 1/20 0.56
CYP2C19 P33261 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
HSD17B10 Q99714 1/20 0.56
GAA P10253 1/20 0.56
PARP15 Q460N3 3/20 0.53
PARP10 Q53GL7 3/20 0.53
TNKS O95271 1/20 0.52
PARP14 Q460N5 1/20 0.52
TNKS2 Q9H2K2 1/20 0.52
PARP2 Q9UGN5 1/20 0.52
BRD4 O60885 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL180075 1.00 PARP1 (0.64) PARP1TSHRTDP1L3MBTL1POLB
Cyclohexane SCHEMBL9229438 0.98 PARP1 (0.61) PARP1TSHRTDP1L3MBTL1POLB
Terephthalamide SCHEMBL4985044 0.95 PARP1 (0.59) PARP1TSHRTDP1L3MBTL1POLB
SCHEMBL31021028 0.92 PARP1 (0.73) PARP1TSHRTDP1L3MBTL1POLB
SCHEMBL36694 0.92 PARP1 (0.73) PARP1TSHRTDP1L3MBTL1POLB
Hydrochloric Acid SCHEMBL1367509 0.90 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Water SCHEMBL7768285 0.90 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Ammonia Solution, Strong SCHEMBL9121446 0.90 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Methane SCHEMBL688609 0.90 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Terephthalamide SCHEMBL5692322 0.87 PARP1 (0.67) PARP1TSHRTDP1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0411709-B1 Polyamide composition DSM NV (NL) 1994-06-01 EP claimed
EP-0270146-B1 COPOLYAMIDE AND A PROCESS FOR THE PREPARATION THEREOF DSM N.V. (NL) 1992-09-23 EP claimed
US-5084552-A Tetramethylenediamine with adipic acid, terephthalic acid and isophthalic acid terpolyamide for moldings and films STAMICARBON B.V. (NL) 1992-01-28 US claimed
EP-0411709-A1 Polyamide composition DSM N.V. (NL) 1991-02-06 EP claimed
EP-0270146-A1 Copolyamide and a process for the preparation thereof DSM N.V. (NL) 1988-06-08 EP claimed
EP-0247203-A1 POLYAMIDE PACKAGING MATERIAL TEIJIN LIMITED (JP) 1987-12-02 EP claimed
WO-1987002680-A2 POLYAMIDE PACKAGING MATERIAL TEIJIN LIMITED (JP) 1987-05-07 WO claimed
JP-62106926-A None JP disclosed
CN-109689785-B Thermoplastic resin composition and molded article thereof 东丽株式会社 2021-10-01 CN disclosed
CN-108350268-B Heat aging resistant polyamide resin composition and method for improving heat aging resistance of polyamide resin 东洋纺株式会社 2021-02-19 CN disclosed
CN-106232727-B Polyamide resin composition, polyamide resin composition particle group, molded body, and method for producing polyamide resin composition 旭化成株式会社 2020-09-22 CN disclosed
WO-2020137128-A1 LAMINATE 宇部興産株式会社 2020-07-02 WO disclosed
CN-111183174-A Glass fiber reinforced resin molded article 日东纺绩株式会社 2020-05-19 CN disclosed
EP-0270146-A1 Copolyamide and a process for the preparation thereof DSM N.V. (NL) 1988-06-08 EP disclosed
WO-1987002680-A3 POLYAMIDE PACKAGING MATERIAL TEIJIN LTD (JP) 1988-03-24 WO disclosed
EP-0247203-A1 POLYAMIDE PACKAGING MATERIAL TEIJIN LIMITED (JP) 1987-12-02 EP disclosed
JP-S62106926-A POLYAMIDE PACKAGING MATERIAL TEIJIN LTD 1987-05-18 JP disclosed
WO-1987002680-A2 POLYAMIDE PACKAGING MATERIAL TEIJIN LIMITED (JP) 1987-05-07 WO disclosed
WO-1987002680-A2 POLYAMIDE PACKAGING MATERIAL TEIJIN LIMITED (JP) 1987-05-07 WO disclosed
EP-0219973-A2 Impact resistant polyamide compositions Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-04-29 EP disclosed