Methane

Methane

SCHEMBL688609

C.NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.70
TSHR P16473 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
POLB P06746 1/20 0.62
CYP3A4 P08684 1/20 0.62
MAPT P10636 1/20 0.62
CYP2C19 P33261 1/20 0.62
RECQL P46063 1/20 0.62
BLM P54132 1/20 0.62
PMP22 Q01453 1/20 0.62
HSD17B10 Q99714 1/20 0.62
PARP15 Q460N3 2/20 0.55
PARP10 Q53GL7 2/20 0.55
TNKS O95271 1/20 0.55
PARP14 Q460N5 1/20 0.55
TNKS2 Q9H2K2 1/20 0.55
PARP2 Q9UGN5 1/20 0.55
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36694 0.97 PARP1 (0.73) PARP1TSHRTDP1L3MBTL1POLB
SCHEMBL31021028 0.97 PARP1 (0.73) PARP1TSHRTDP1L3MBTL1POLB
Hydrochloric Acid SCHEMBL1367509 0.94 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Ammonia Solution, Strong SCHEMBL9121446 0.94 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Water SCHEMBL7768285 0.94 PARP1 (0.70) PARP1TSHRTDP1L3MBTL1POLB
Terephthalamide SCHEMBL5692322 0.92 PARP1 (0.67) PARP1TSHRTDP1L3MBTL1POLB
SCHEMBL10458793 0.90 PARP1 (0.64) PARP1TSHRTDP1L3MBTL1POLB
Thiourea SCHEMBL28810017 0.90 PARP1 (0.64) PARP1TSHRTDP1L3MBTL1POLB
Cyclohexane SCHEMBL180075 0.90 PARP1 (0.64) PARP1TSHRTDP1L3MBTL1POLB
SCHEMBL2831672 0.90 PARP1 (0.64) PARP1TSHRTDP1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156838-A Polyamide resin composition and process for producing the same UNITIKA LTD. (JP) 2000-12-05 US claimed
EP-4299541-A1 GLASS COMPOSITION FOR GLASS FIBERS, GLASS FIBER, AND GLASS FIBER-REINFORCED RESIN MOLDED ARTICLE Nitto Boseki Co., Ltd. (JP) 2024-01-03 EP disclosed
EP-1394214-B1 POLYAMIDE RESIN COMPOSITION FOR FUSE DEVICE PACIFIC ENGINEERING CORP (JP) 2012-02-29 EP disclosed
EP-1394214-A1 POLYAMIDE RESIN COMPOSITION FOR FUSE DEVICE Pacific Engineering Corporation (JP) 2004-03-03 EP disclosed
EP-0542536-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1996-10-16 EP disclosed
EP-0542536-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-19 EP disclosed