Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12303232 | 0.79 | GLA (0.50) | GLAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8583388 | 0.78 | IDO1 (0.41) | MAOB | |
| SCHEMBL14426952 | 0.78 | GLA (0.47) | GLAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2401047 | 0.77 | GLA (0.51) | GLAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29482067 | 0.76 | KMT2A (0.53) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2383968 | 0.76 | KMT2A (0.53) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28243335 | 0.75 | KMT2A (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2157445 | 0.75 | ALDH1A1 (0.55) | GLAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5986932 | 0.74 | MRGPRX4 (0.48) | GLASCN8AMAOBMAOAFFAR1 | |
| SCHEMBL4636453 | 0.74 | GLA (0.49) | GLAALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619693-B | The alternatively indoles nitrile of property androgen receptor modifier | 葛兰素史克知识产权第二有限公司 | 2019-08-13 | — | — | CN | disclosed |