Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487568 | 0.85 | HTR2C (0.45) | HTR2CMAOAMAOBSCN9AHTR2A | |
| SCHEMBL29481964 | 0.77 | MAOB (0.42) | HTR2CMAOAMAOBSCN9AHTR2A | |
| SCHEMBL21306626 | 0.77 | MAOB (0.42) | HTR2CMAOAMAOBSCN9AHTR2A | |
| SCHEMBL29481962 | 0.77 | MAOB (0.42) | HTR2CMAOAMAOBSCN9AHTR2A | |
| SCHEMBL20063742 | 0.77 | MAOB (0.42) | HTR2CMAOAMAOBSCN9AHTR2A | |
| SCHEMBL21294962 | 0.77 | MAOB (0.42) | HTR2CMAOAMAOBSCN9AHTR2A | |
| SCHEMBL21294928 | 0.76 | HTR2C (0.43) | HTR2CMAOBSCN9AHTR2AHTR2B | |
| SCHEMBL21294734 | 0.76 | HTR2C (0.43) | HTR2CMAOBSCN9AHTR2AHTR2B | |
| SCHEMBL21306739 | 0.76 | HTR2C (0.43) | HTR2CMAOBSCN9AHTR2AHTR2B | |
| SCHEMBL21294829 | 0.75 | HTR2C (0.42) | HTR2CMAOAMAOBGUSBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072855-A | Therapeutic compound and its application method | 基因泰克公司 | 2019-07-30 | — | — | CN | disclosed |