Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487441 | 0.86 | SCN9A (0.47) | HTR2CTACR1SCN9A | |
| SCHEMBL28319367 | 0.85 | HTR2C (0.40) | HTR2CMAOAMAOBHTR2AHTR2B | |
| SCHEMBL28487048 | 0.84 | SCN9A (0.46) | HTR2CTACR1DRD2TRPM5SCN9A | |
| SCHEMBL28487582 | 0.82 | SCN9A (0.49) | HTR2CDRD2SCN9A | |
| SCHEMBL28493110 | 0.82 | HTR2C (0.40) | HTR2CTACR1HTR2AHTR2BDRD2 | |
| SCHEMBL28500202 | 0.82 | SCN9A (0.44) | HTR2CTACR1SCN9A | |
| SCHEMBL21296542 | 0.81 | HTR2C (0.54) | HTR2CHTR2AHTR2BDRD2GUSB | |
| SCHEMBL28503005 | 0.81 | SCN9A (0.39) | HTR2CTACR1HTR2AHTR2BDRD2 | |
| SCHEMBL28494267 | 0.80 | SCN9A (0.37) | MAOAMAOBTACR1KDM1ASCN9A | |
| SCHEMBL28495980 | 0.78 | SCN9A (0.47) | TACR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041313-A | Pyridine-sulfonamide compounds and their use against pain and related conditions | 基因泰克公司 | 2020-12-04 | — | — | CN | disclosed |