Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15014207 | 1.00 | APP (0.67) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10091202 | 1.00 | APP (0.67) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9715641 | 0.97 | APP (0.63) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15014219 | 0.93 | CYP1A2 (0.58) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9445826 | 0.88 | GRM5 (0.64) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4457730 | 0.88 | GRM5 (0.64) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15014176 | 0.87 | CYP1A1 (0.64) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9715647 | 0.85 | GRM5 (0.61) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2114741 | 0.85 | APP (0.92) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20886673 | 0.85 | CA12 (0.53) | APPALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005476-B | Synthesis of 1-methyl-4- (phenylethynyl) benzene by palladium catalysis of tetrafluorothianthrene salt | 内蒙古大学 | 2025-04-11 | — | — | CN | claimed |
| CN-118005476-A | Synthesis of 1-methyl-4- (phenylethynyl) benzene by palladium catalysis of tetrafluorothianthrene salt | 内蒙古大学 | 2024-05-10 | — | — | CN | claimed |
| CN-117845235-A | Preparation method of cis-stilbene compound | 深圳市环保科技集团股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117820365-A | Thiophosphine (phosphate) and preparation method thereof | 烟台新药创制山东省实验室 | 2024-04-05 | — | — | CN | claimed |
| EP-1310487-B1 | PROCESSES FOR PREPARATION OF BICYCLIC COMPOUNDS AND INTERMEDIATES THEREFOR | DAIICHI SEIYAKU CO (JP) | 2007-01-03 | — | — | EP | claimed |
| EP-0044158-B1 | NOVEL OPTICALLY ACTIVE IMIDAZOLIDIN-2-ONE DERIVATIVES AND THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-15 | — | — | EP | claimed |
| CN-116410126-B | Ligand, ruthenium complex, preparation method thereof and application of ligand and ruthenium complex in catalyzing alkyne semi-hydrogenation reaction | 河北师范大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-118005476-B | Synthesis of 1-methyl-4- (phenylethynyl) benzene by palladium catalysis of tetrafluorothianthrene salt | 内蒙古大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-118005476-B | Synthesis of 1-methyl-4- (phenylethynyl) benzene by palladium catalysis of tetrafluorothianthrene salt | 内蒙古大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-118005476-B | Synthesis of 1-methyl-4- (phenylethynyl) benzene by palladium catalysis of tetrafluorothianthrene salt | 内蒙古大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-113825735-B | Carbon-carbon bond formation method | 奥加诺株式会社 | 2025-01-07 | — | — | CN | disclosed |
| CN-118126054-A | Coumarin derivative modified donor-acceptor type high polymer material and preparation method and application thereof | 长安大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-118005476-A | Synthesis of 1-methyl-4- (phenylethynyl) benzene by palladium catalysis of tetrafluorothianthrene salt | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| EP-1654219-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2006-05-10 | — | — | EP | disclosed |
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | DSM N.V. (NL) | 2005-06-23 | — | — | US | disclosed |
| WO-2005012232-A2 | HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |
| US-5043510-A | Aqueous alkylation process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-08-27 | — | — | US | disclosed |
| US-4427595-A | Catalyst composition to effect metathesis of acetylenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1984-01-24 | — | — | US | disclosed |
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137402-A1 | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds | NAT1, B3GNT2, NISCH | APP 1495/4885ALDH1A1 2327/4885MAPT 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.