Idebenone

Idebenone

SCHEMBL28320

COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
LMNA P02545 2/20 1.00
PGR P06401 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
MAOA P21397 1/20 1.00
TBXA2R P21731 1/20 1.00
MAPK1 P28482 1/20 1.00
AVPR2 P30518 1/20 1.00
CYP2C19 P33261 1/20 1.00
HTR2B P41595 1/20 1.00
HTT P42858 1/20 1.00
PDE3A Q14432 1/20 1.00
SIRT2 Q8IXJ6 1/20 1.00
SLC29A1 Q99808 1/20 1.00
ALDH1A1 P00352 1/20 0.73
THRB P10828 1/20 0.73
TRAP1 Q12931 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7407419 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL7404132 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL7408250 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL7408049 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL1242543 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL19799191 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL7415134 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
Idebenone SCHEMBL10515979 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL7416961 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4
SCHEMBL7416239 1.00 MAPT (1.00) MAPTTDP1LMNAPGRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9975 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080099-A Amphiphilic nicotinamide adenine dinucleotide conjugate, nano micelle and application thereof 2026-05-26 CN claimed
CN-116850073-B Active substance eutectic solvent liposome face cream and preparation method thereof 北京理工大学重庆创新中心 2026-05-19 CN claimed
CN-122056786-A Lipid hybridization nanoparticle and preparation method and application thereof 上海世领制药有限公司 2026-05-19 CN claimed
CN-122011028-A Method for efficiently preparing various substituted chiral phosphoramides 上海交通大学 2026-05-12 CN claimed
US-20260126444-A1 Biomarkers for Long COVID UNIV SZEGEDI (HU) 2026-05-07 US claimed
EP-4709421-A2 B. BURGDORFERI PEPTIDOGLYCAN ANTIBODIES AND USES THEREOF Virginia Tech Intellectual Properties, Inc. (US) 2026-03-18 EP claimed
EP-4705487-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISORDERS RELATED TO FRATAXIN DEFICIENCY Voyager Therapeutics, Inc. (US) 2026-03-11 EP claimed
CN-121570368-A Micelle dispersion liquid 厦门瑞聚医学科技有限公司 2026-02-27 CN claimed
US-20260053750-A1 INHALABLE COMPOSITIONS OF CDK9 INHIBITORS OWEN MATTHEW (US) 2026-02-26 US claimed
US-20250382291-A1 SUBSTITUTED PYRROLO[2,3-b]PYRIDINES FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS UNIV COLUMBIA (US) 2025-12-18 US claimed
US-4525361-A FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-06-25 US claimed
US-4514420-A Antifibrotic agent TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-04-30 US claimed
EP-0045126-B1 CATALYTIC PROCESS FOR PRODUCING HYDROGEN IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-05 EP claimed
US-4436753-A CARDIOVASCULAR DISORDERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1984-03-13 US claimed
US-4358461-A Antiallergic agent TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-11-09 US claimed
EP-0038674-A1 Medicinal composition for treatment of allergic diseases Takeda Chemical Industries, Ltd. (JP) 1981-10-28 EP claimed
EP-0031727-A2 Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones Takeda Chemical Industries, Ltd. (JP) 1981-07-08 EP claimed
US-4271083-A IMMUNO-POTENTIATING ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-06-02 US claimed
EP-0025375-A1 Circuit breaker with magnetic blow-out means and rotating arc MERLIN GERIN (FR) 1981-03-18 EP claimed
EP-0014646-A1 Method of preparing road surfaces and road surfaces obtained by this method ENTREPRISES ALBERT COCHERY (FR) 1980-08-20 EP claimed