Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | AVPR2 | P30518 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 1/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 1.00 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407419 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7404132 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7408250 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7408049 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL1242543 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL19799191 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7415134 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| Idebenone SCHEMBL10515979 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7416961 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 | |
| Idebenone SCHEMBL28320 | 1.00 | MAPT (1.00) | MAPTTDP1LMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038674-B1 | MEDICINAL COMPOSITION FOR TREATMENT OF ALLERGIC DISEASES | Takeda Chemical Industries, Ltd. (JP) | 1989-08-30 | — | — | EP | claimed |
| US-4358461-A | Antiallergic agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-11-09 | — | — | US | claimed |
| EP-0038674-A1 | Medicinal composition for treatment of allergic diseases | Takeda Chemical Industries, Ltd. (JP) | 1981-10-28 | — | — | EP | claimed |
| EP-0031727-B1 | MEDICINAL COMPOSITIONS COMPRISING AS AN ACTIVE INGREDIENT SUBSTITUTED 1,4-BENZOQUINONES | Takeda Chemical Industries, Ltd. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4559177-A | HYPOTENSIVE, CARDIOTONIC AND ANTIPHYLATIC AGENTS; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-17 | — | — | US | disclosed |
| US-4436753-A | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
| US-4358461-A | Antiallergic agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-11-09 | — | — | US | disclosed |
| EP-0038674-A1 | Medicinal composition for treatment of allergic diseases | Takeda Chemical Industries, Ltd. (JP) | 1981-10-28 | — | — | EP | disclosed |
| EP-0031727-A2 | Medicinal compositions comprising as an active ingredient substituted 1,4-benzoquinones | Takeda Chemical Industries, Ltd. (JP) | 1981-07-08 | — | — | EP | disclosed |
| EP-0021841-A2 | 2,3-Dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |