⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868744 | 0.86 | — | — | |
| SCHEMBL1060673 | 0.70 | — | — | |
| SCHEMBL26011809 | 0.70 | — | — | |
| SCHEMBL15100766 | 0.68 | — | — | |
| SCHEMBL7785889 | 0.68 | — | — | |
| SCHEMBL8255846 | 0.68 | — | — | |
| SCHEMBL14868804 | 0.67 | KDM4E (0.40) | — | |
| SCHEMBL22750790 | 0.67 | GLA (0.38) | — | |
| SCHEMBL19077865 | 0.65 | — | — | |
| SCHEMBL14868780 | 0.64 | FYN (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143963-A | With active pyridazine compound of sterilizing and its preparation method and application | 河南科技大学第一附属医院 | 2019-08-20 | — | — | CN | claimed |
| CN-110143963-A | With active pyridazine compound of sterilizing and its preparation method and application | 河南科技大学第一附属医院 | 2019-08-20 | — | — | CN | disclosed |