Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27998888 | 0.98 | L3MBTL1 (0.42) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| Sulfuric Acid SCHEMBL28423116 | 0.97 | L3MBTL1 (0.41) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| Hydrochloric Acid SCHEMBL29043668 | 0.97 | L3MBTL1 (0.41) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| SCHEMBL27998576 | 0.94 | L3MBTL1 (0.40) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| SCHEMBL28415731 | 0.92 | L3MBTL1 (0.39) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| Cyanide SCHEMBL28324913 | 0.92 | L3MBTL1 (0.39) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL28492046 | 0.90 | KMT2A (0.39) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| Trifluoroacetic Acid SCHEMBL28489578 | 0.87 | KMT2A (0.43) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| SCHEMBL27975187 | 0.86 | L3MBTL1 (0.40) | L3MBTL1KDM4ECYP2D6MAPTTSHR | |
| SCHEMBL28487074 | 0.85 | TSHR (0.44) | L3MBTL1KDM4ECYP2D6MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110064432-A | Short-pore mesoporous silicon supported chloroaluminate ionic liquid catalyst and preparation method thereof | 南京工业大学 | 2019-07-30 | — | — | CN | disclosed |