Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658747 | 0.81 | MEN1 (0.57) | KMT2AMEN1POLBTDP1SMN1; SMN2 | |
| SCHEMBL26342419 | 0.74 | SMN1; SMN2 (0.62) | KMT2AMEN1RECQLPOLBL3MBTL1 | |
| SCHEMBL14918268 | 0.73 | PTGS1 (0.63) | KMT2AMEN1L3MBTL1PTGS1SMN1; SMN2 | |
| SCHEMBL14918967 | 0.73 | RARG (0.47) | KMT2AMEN1PTGS1ALDH1A1HTT | |
| SCHEMBL28103577 | 0.73 | CCNA2 (0.52) | KMT2AMEN1RECQLPTGS1SMN1; SMN2 | |
| SCHEMBL28103551 | 0.73 | CCNA2 (0.52) | KMT2AMEN1RECQLPTGS1SMN1; SMN2 | |
| SCHEMBL28103553 | 0.73 | CCNA2 (0.52) | KMT2AMEN1RECQLPTGS1SMN1; SMN2 | |
| SCHEMBL12670655 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1POLBTDP1L3MBTL1 | |
| SCHEMBL5698596 | 0.72 | ALDH1A1 (0.60) | RECQLPOLBTDP1L3MBTL1PTGS1 | |
| SCHEMBL26342422 | 0.71 | MEN1 (0.62) | KMT2AMEN1RECQLPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103933032-B | The application method and purposes of pyrazole derivatives as anticancer drug | 北京赛林泰医药技术有限公司 | 2019-08-23 | — | — | CN | disclosed |