Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321646 | 0.99 | HPGD (0.66) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL13309949 | 0.82 | HPGD (1.00) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL28321647 | 0.77 | HPGD (0.68) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL28876756 | 0.76 | HPGD (0.67) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL16402980 | 0.76 | HPGD (0.62) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL28320586 | 0.75 | HPGD (0.66) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL26070211 | 0.75 | LMNA (0.78) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL28321640 | 0.74 | HPGD (0.64) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL16403170 | 0.74 | HPGD (0.60) | HPGDMAPTTSHRHSD17B10HTT | |
| SCHEMBL13111332 | 0.74 | HPGD (0.72) | HPGDMAPTTSHRHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | claimed |
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |