Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990343 | 0.85 | SLC7A5 (0.54) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL15705312 | 0.84 | KMT2A (0.47) | KMT2AMEN1TSHRPTGS1PTGS2 | |
| SCHEMBL28370252 | 0.84 | PTGS1 (0.55) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL28320750 | 0.82 | SLC7A5 (0.51) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL3937986 | 0.82 | SLC7A5 (0.55) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8186958 | 0.81 | SLC7A5 (0.56) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL27649234 | 0.79 | SLC7A5 (0.54) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL12400239 | 0.79 | SLC7A5 (0.68) | SLC7A5ALDH1A1GAAGFERHSP90AB1 | |
| SCHEMBL21839394 | 0.78 | SLC7A5 (0.52) | SLC7A5KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1560308 | 0.76 | SLC7A5 (0.65) | SLC7A5ALDH1A1GAAGFERHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272392-A | Transition metal catalyzed C-H coupling for efficiently preparing 2- (4(3H) -quinazolinone) aryl alkyl acetate derivative | 四川大学 | 2019-09-24 | — | — | CN | disclosed |