Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.68 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394735 | 0.94 | SLC7A5 (0.62) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL1560308 | 0.92 | SLC7A5 (0.65) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL7718934 | 0.92 | SLC7A5 (0.60) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL694460 | 0.92 | SLC7A5 (0.65) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL12508635 | 0.92 | SLC7A5 (0.60) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL480042 | 0.91 | SLC7A5 (0.59) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL5552116 | 0.91 | SLC7A5 (0.59) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL8655484 | 0.91 | SLC7A5 (0.59) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL335779 | 0.91 | SLC7A5 (0.59) | SLC7A5HSP90AB1ALDH1A1GAAGFER | |
| SCHEMBL5046679 | 0.91 | SLC7A5 (0.63) | SLC7A5HSP90AB1ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170951-A1 | AMIDE-LINKED EP4 AGONIST-BISPHOSPHONATE COMPOUNDS AND USES THEREOF | SIMON FRASER UNIVERSITY (CA) | 2018-06-21 | — | — | US | disclosed |
| EP-2764866-A1 | Inhibitors of nedd8-activating enzyme | IP Gesellschaft für Management mbH (DE) | 2014-08-13 | — | — | EP | disclosed |
| EP-2764866-A1 | Inhibitors of nedd8-activating enzyme | IP Gesellschaft für Management mbH (DE) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013021309-A1 | INTERMEDIATE AND PROCESS FOR THE PREPARATION OF A SULFONAMIDE DERIVATIVE | PFIZER LIMITED (GB) | 2013-02-14 | — | — | WO | disclosed |
| WO-2013021309-A1 | INTERMEDIATE AND PROCESS FOR THE PREPARATION OF A SULFONAMIDE DERIVATIVE | PFIZER LIMITED (GB) | 2013-02-14 | — | — | WO | disclosed |
| US-20110184105-A1 | Phenylene Oxo-Diester Plasticizers and Methods of Making | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110184105-A1 | Phenylene Oxo-Diester Plasticizers and Methods of Making | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-07-28 | — | — | US | disclosed |
| WO-2011041349-A1 | PHENYLENE OXO-DIESTER PLASTICIZERS AND METHODS OF MAKING | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20070231754-A1 | Black and white photothermographic material | FUJIFILM CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-20070196778-A1 | Black and white photothermographic material | FUJIFILM CORPORATION | 2007-08-23 | — | — | US | disclosed |
| US-20070196779-A1 | Black and white photothermographic material | FUJIFILM CORPORATION | 2007-08-23 | — | — | US | disclosed |
| US-20070196777-A1 | Black and white photothermographic material | FUJIFILM CORPORATION | 2007-08-23 | — | — | US | disclosed |
| US-20070065764-A1 | Black and white photothermographic material and image forming method | FUJI PHOTO FILM CO., LTD. | 2007-03-22 | — | — | US | disclosed |
| US-20070065763-A1 | Photothermographic material | FUJI PHOTO FILM CO., LTD. | 2007-03-22 | — | — | US | disclosed |
| US-20070065762-A1 | Black and white photothermographic material and image forming method | FUJI PHOTO FILM CO., LTD. | 2007-03-22 | — | — | US | disclosed |
| US-20070031765-A1 | Black and white photothermographic material | FUJI PHOTO FILM CO., LTD. | 2007-02-08 | — | — | US | disclosed |
| US-20070026348-A1 | Black and white photothermographic material and image forming method | FUJI PHOTO FILM CO., LTD. | 2007-02-01 | — | — | US | disclosed |
| US-20070003885-A1 | Black and white photothermographic material and image forming method | FUJI PHOTO FILM CO., LTD. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170951-A1 | AMIDE-LINKED EP4 AGONIST-BISPHOSPHONATE COMPOUNDS AND USES THEREOF | PTGER4, ENPP2, PTGER3 | SLC7A5 2071/4885HSP90AB1 3464/4885ALDH1A1 2130/4885 |
| US-20110184105-A1 | Phenylene Oxo-Diester Plasticizers and Methods of Making | HPD, DDT, PAOX | SLC7A5 4750/4885HSP90AB1 4176/4885ALDH1A1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.