Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30534232 | 0.88 | GRIN2D (0.62) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL5328724 | 0.85 | GRIN2D (0.68) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL28740338 | 0.84 | GRIN2D (0.47) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL9765029 | 0.84 | GRIN2D (0.70) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL22222298 | 0.80 | GRIN2D (0.50) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL27525123 | 0.75 | SLC6A4 (0.51) | OPRM1OPRL1SLC6A4SLC6A2SLC6A3 | |
| Eticyclidine SCHEMBL66697 | 0.75 | GRIN2D (0.57) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL29728985 | 0.74 | GRIN2D (0.61) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| Eticyclidine SCHEMBL10669385 | 0.74 | GRIN2D (0.58) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B | |
| SCHEMBL7375815 | 0.72 | GRIN2D (0.62) | GRIN1GRIN2AGRIN2BGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172058-B | 7-azaspiro [5.6] dodecane-10-one compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | claimed |
| CN-110172058-A | 7- azaspiro [5.6] dodecane -10- ketone compounds and preparation method thereof and purposes | 中国医科大学 | 2019-08-27 | — | — | CN | claimed |
| CN-110172058-B | 7-azaspiro [5.6] dodecane-10-one compound and preparation method and application thereof | 中国医科大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-110172058-A | 7- azaspiro [5.6] dodecane -10- ketone compounds and preparation method thereof and purposes | 中国医科大学 | 2019-08-27 | — | — | CN | disclosed |