Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.70 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.70 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.70 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.70 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.70 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.70 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.70 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.70 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.70 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.70 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328724 | 0.92 | GRIN2D (0.68) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL30534232 | 0.85 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL19242764 | 0.84 | GRIN2D (0.97) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL28320786 | 0.84 | GRIN1 (0.55) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL3504791 | 0.82 | GRIN2D (0.49) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Bromide SCHEMBL20501902 | 0.81 | GRIN2D (0.97) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| Hydrochloric Acid SCHEMBL5312402 | 0.80 | GRIN2D (0.52) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL29728985 | 0.80 | GRIN2D (0.61) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL5153683 | 0.79 | GRIN2D (0.46) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL22222298 | 0.79 | GRIN2D (0.50) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |