Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMO | Q99835 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319645 | 1.00 | KMT2A (0.72) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL25296052 | 0.98 | KMT2A (0.70) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL29180170 | 0.98 | KMT2A (0.70) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL19933569 | 0.92 | MEN1 (0.82) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL29730468 | 0.88 | KMT2A (0.61) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL18732403 | 0.88 | KMT2A (0.61) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL18731741 | 0.88 | KMT2A (0.61) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL21003801 | 0.88 | KMT2A (0.61) | KMT2AMEN1MAPTMAP4K4SMN1; SMN2 | |
| SCHEMBL190954 | 0.88 | AURKA (0.63) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29620532 | 0.88 | AURKA (0.63) | KMT2AMEN1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693499-A | Compound, material for organic electroluminescent element, and electronic device | 出光兴产株式会社 | 2024-03-12 | — | — | CN | disclosed |
| CN-114555566-A | Organic compound and organic electroluminescent element comprising same | 索路思高新材料有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108409672-B | Method for synthesizing polysubstituted pyrimidine under catalysis of copper salt | 安徽师范大学 | 2020-01-10 | — | — | CN | disclosed |
| CN-106496127-B | A kind of preparation method of polysubstituted pyrimidine | 苏州大学 | 2019-09-27 | — | — | CN | disclosed |