Acrylic Acid

Acrylic Acid

SCHEMBL28320855

C=CC(=O)O.CCCC[Si](OC)(OC)OC

nearest known ligand 0.42

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
HCAR2 Q8TDS4 3/20 0.35
FAAH O00519 1/20 0.33
EPHX1 P07099 1/20 0.33
THRB P10828 2/20 0.33
ALDH1A1 P00352 1/20 0.32
THRA P10827 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28320854 0.93 LMNA (0.47) LMNATSHRHPGDZDHHC20ZDHHC2
Acrylic Acid SCHEMBL15876790 0.88 LMNA (0.42) LMNATSHRHPGDZDHHC20ZDHHC2
Acrylic Acid SCHEMBL28330565 0.83 LMNA (0.37) LMNATSHRTHRBALOX15HSD17B10
Acetic Acid SCHEMBL21330589 0.82 LMNA (0.46) LMNATSHREPHX1ALDH1A1ALOX15
SCHEMBL1012383 0.81 TSHR (0.47) LMNATSHRHPGDZDHHC20ZDHHC2
SCHEMBL27784237 0.80 TSHR (0.38) LMNATSHRHPGDZDHHC20ZDHHC2
Acrylic Acid SCHEMBL29165216 0.80 LMNA (0.42) LMNATSHRALDH1A1ALOX15HSD17B10
Acrylic Acid SCHEMBL29139304 0.79 TSHR (0.53) LMNATSHRHPGDHCAR2THRB
SCHEMBL56908 0.78 LMNA (0.58) LMNATSHREPHX1THRB
Benzene SCHEMBL27743707 0.77 LMNA (0.52) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156998-A Cage modle polysilsesquioxane-polyethylene glycol polymer solid electrolyte material and preparation method thereof 洛阳理工学院 2019-08-23 CN disclosed