Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321737 | 0.81 | IDO1 (0.59) | IDO1NFE2L2 | |
| SCHEMBL28321701 | 0.80 | NFE2L2 (0.43) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL17969098 | 0.78 | ERBB2 (0.47) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL17969097 | 0.78 | ERBB2 (0.47) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL28320564 | 0.78 | NFE2L2 (0.43) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL16399363 | 0.73 | NFE2L2 (0.39) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL16399364 | 0.73 | NFE2L2 (0.39) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL18002906 | 0.72 | NFE2L2 (0.54) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL21944615 | 0.72 | PTGS1 (0.56) | NFE2L2CYP1A1CYP1B1PTGS1PTGS2 | |
| SCHEMBL28321695 | 0.72 | IDO1 (0.41) | IDO1NFE2L2NOTUMPTGS1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |