Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 7/20 | 0.51 |
| ▸ | METAP2 | P50579 | 6/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320545 | 0.82 | IDO1 (0.58) | NOTUMMRGPRX4IDO1METAP2NR1H2 | |
| SCHEMBL28320824 | 0.81 | NR1H2 (0.39) | MRGPRX4NR1H2NR1H3 | |
| SCHEMBL28876791 | 0.77 | NR1H2 (0.40) | MRGPRX4NR1H2NR1H3 | |
| SCHEMBL16397726 | 0.76 | ERBB2 (0.44) | MRGPRX4NR1H2NR1H3PHF8 | |
| SCHEMBL21792289 | 0.76 | NOTUM (1.00) | NOTUMIDO1METAP2 | |
| SCHEMBL21944599 | 0.73 | APP (0.56) | MRGPRX4 | |
| SCHEMBL28320555 | 0.72 | MRGPRX4 (0.67) | NOTUMMRGPRX4IDO1METAP2PHF8 | |
| SCHEMBL16399337 | 0.72 | NR1H2 (0.38) | MRGPRX4NR1H2NR1H3 | |
| SCHEMBL16399407 | 0.71 | CYP11B1 (0.39) | MRGPRX4NR1H2NR1H3 | |
| SCHEMBL22469872 | 0.70 | MRGPRX4 (1.00) | MRGPRX4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |