SCHEMBL16399337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18006409	0.91	NR1H2 (0.40)	NR1H2NR1H3KDM4EMEN1ALDH1A1
	SCHEMBL18004043	0.91	IDO1 (0.41)	NR1H2NR1H3CYP11B1CYP11B2MRGPRX4
	SCHEMBL18004294	0.87	PTGDR2 (0.32)	NR1H2KDM4EMEN1ALDH1A1MAPT
	SCHEMBL18003993	0.86	NR4A2 (0.50)	NR1H2NR1H3MAPTMRGPRX4MAOB
	SCHEMBL18004436	0.85	NR4A2 (0.41)	NR1H2NR1H3KDM4EMEN1ALDH1A1
	SCHEMBL18004906	0.84	CYP11B1 (0.40)	KDM4EMEN1ALDH1A1MAPTPPARG
	SCHEMBL16399407	0.84	CYP11B1 (0.39)	NR1H2NR1H3KDM4EMEN1ALDH1A1
	SCHEMBL18004689	0.84	MRGPRX4 (0.47)	NR1H2NR1H3MAPTMRGPRX4MAOB
	SCHEMBL18003995	0.84	IGF1R (0.43)	KDM4EMEN1ALDH1A1MAPTPPARG
	SCHEMBL16399235	0.84	NR1H2 (0.42)	NR1H2NR1H3KDM4EPGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.