SCHEMBL28322012

SCHEMBL28322012

Nc1c(C(=O)O)oc2c1ccc1ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.68
KDM4E B2RXH2 6/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
ABCG2 Q9UNQ0 4/20 0.52
ALDH1A1 P00352 5/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 4/20 0.46
HSD17B10 Q99714 3/20 0.46
HTT P42858 3/20 0.46
TSHR P16473 2/20 0.46
GLA P06280 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP1A2 P05177 4/20 0.44
CYP1A1 P04798 3/20 0.44
CYP1B1 Q16678 3/20 0.44
PRKDC P78527 2/20 0.44
ABCC1 P33527 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13699673 0.87 HPGD (0.55) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL11743090 0.81 KDM4E (1.00) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL30080983 0.79 KDM4E (0.65) HPGDKDM4EL3MBTL1ALDH1A1LMNA
SCHEMBL11746188 0.78 HPGD (0.68) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL28323071 0.77 L3MBTL1 (0.55) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL11747022 0.77 HPGD (0.67) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL2774740 0.74 MAPT (0.72) HPGDKDM4EALDH1A1MAPTHTT
SCHEMBL5470220 0.70 HPRT1 (0.57) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL30154375 0.70 HPRT1 (0.57) HPGDKDM4EL3MBTL1ABCG2ALDH1A1
SCHEMBL8054422 0.70 KDM4E (0.61) HPGDKDM4EL3MBTL1ABCG2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115696945-A Light emitting device 株式会社半导体能源研究所 2023-02-03 CN disclosed
CN-110382502-B Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2022-11-29 CN disclosed
CN-110382502-A ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE 株式会社半导体能源研究所 2019-10-25 CN disclosed